The Difference Between On Label and Off Label Conditions


You may be wondering about the conditions we've seen at Hyperbaric Medical Solutions (HMS).

You’ll typically see them grouped into two categories: on label and off label.

So what exactly does that difference mean? Let us explain:

On Label Conditions:

Basically, on label conditions are those that the FDA has approved for treatment so they'll likely be covered by Medicare and other commercial insurance companies.

HMS on label conditions are as follows:

Air or Gas Embolism

Carbon Monoxide Poisoning or Smoke Inhalation

Central Retinal Artery Occlusion

Chronic Refractory Osteomyelitis

Crush Injury, Compartment Syndrome and Other Acute Traumatic Ischemias

Decompression Sickness

Diabetic Lower Extremity Wounds

Failed Skin Grafts and Flaps

Gas Gangrene

Necrotizing Soft Tissue Infections

Non-Healing Wounds

Radiation Tissue Damage

Severe Anemia

Sudden Sensorineural Hearing Loss Treatment

Thermal Burns


Off Label Conditions:

Off label refers to those conditions that the FDA has not yet approved for a certain treatment, although the conditions may have been studied and documented by research; and studies may be ongoing. In many cases, their treatment may be approved by regulatory bodies in other countries. In general, off label conditions in the U.S. are not covered by insurance. The conditions seen at HMS that are currently considered off label are only those with documented efficacy and it is explained to each of these patients that treatment for their particular condition is not yet recognized by the FDA.

HMS off label Conditions are as follows:

Anoxic Brain Injury

Cancer (Treatment Synergy)

Cerebral Palsy

Chronic Fatigue Syndrome

Chronic Pain

Complex Regional Pain Syndrome (CRPS/RSD)

Concussion & Traumatic Brain Injury

Crohn’s Disease


Inflammatory Bowel Syndrome

Interstitial Cystitis

Lyme Disease


Multiple Sclerosis

Retinitis Pigmentosa

Rheumatoid Arthritis


Spinal Cord Injuries

Sports Injuries


Surgery Preparation & Recovery

Complications of Scleroderma

Ulcerative Colitis


Would you like to learn even more about these conditions? Fill out this form, and one of our staff members will be happy to assist you!


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